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Honorable Anastazia James Wambura is a three-term Member of Parliament having been appointed to a special seat reserved for women.

Honorable MP Wambura became involved with CCM in 2005 and has served in a number of party roles including as a member of the national general meeting. She was appointed to a seat in the Tanzanian Parliament in 2005 to a seat reserved for women. She has been reappointed a further two times in 2010 and 2015. In Parliament, she served as a member of the Natural Resources and Environment Committee between 2006 and 2010, Foreign Affairs, Defense and Security Committee between 2011 and 2013, and Foreign Affairs and International Cooperation Committee. Honorable MP Wambura was appointed Deputy Minister in the Ministry for Information, Culture, Arts and Sports in the newly elected President John Magufuli's government after the 2015 elections. She serves under cabinet Minister Nape Nnauye.